A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of ????,????′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K????CO????

A Facile Synthesis of New 2-Amino-4H-pyran-3-carbonitriles by a One-Pot Reaction of ????,????′-Bis(arylidene) Cycloalkanones and Malononitrile in the Presence of K????CO????

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A rapid and environmentally friendly method is developed for the synthesis of a series here of new substituted 2-amino-4H-pyran-3-carbonitriles through a one-pot condensation of malononitrile and ????,????-bis(arylidene) cycloalkanones in ethanol by using K2CO3 as a catalyst.Short experimental reaction times, excellent yields, no need to use cumbersome apparatus for purification hydrangea red sensation of the products, and inexpensiveness and commercially availability of the catalyst are the advantages of this method.